GSK 951A

CAS No. 1403602-33-4

GSK 951A( GSK951A | GSK-951A )

Catalog No. M11687 CAS No. 1403602-33-4

A small molecule with bactericidal efficacy against Mycobacterium tuberculosis with H37Rv MIC of 0.16 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
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Biological Information

  • Product Name
    GSK 951A
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule with bactericidal efficacy against Mycobacterium tuberculosis with H37Rv MIC of 0.16 uM.
  • Description
    A small molecule with bactericidal efficacy against Mycobacterium tuberculosis with H37Rv MIC of 0.16 uM; suppresses mycolic acid synthesis and EchA6 is essential, and are bactericidal in mouse model of chronic tuberculosis infection.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    GSK951A | GSK-951A
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1403602-33-4
  • Formula Weight
    472.468
  • Molecular Formula
    C24H23F3N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=C2N[C@@H](C3=CC=C(CC)C=C3)C[C@@H](C(F)(F)F)N2N=C1)NCC4=C5OCOC5=CC=C4
  • Chemical Name
    (5R,7S)-N-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(4-ethylphenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cox JA, et al. Nat Microbiol. 2016 Jan 18;1:15006. 2. Remui?án MJ, et al. PLoS One. 2013 Apr 17;8(4):e60933.
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