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Sildenafil
CAS No. 139755-83-2
Sildenafil( —— )
Catalog No. M11659 CAS No. 139755-83-2
Sildenfail is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 49 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSildenafil
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NoteResearch use only, not for human use.
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Brief DescriptionSildenfail is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH).
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DescriptionSildenfail is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH). Sildenafil elevates levels of the second messenger, cGMP, by inhibiting its breakdown via phosphodiesterase type 5 (PDE5). PDE5 is found in particularly high concentrations in the corpus cavernosum, erectile tissue of the penis. It is also found in the retina and vascular endothelium. Increased cGMP results in vasodilation which facilitates generation and maintenance of an erection. The vasodilatory effects of sildenafil also help reduce symptoms of PAH.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE5
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number139755-83-2
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Formula Weight474.58
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Molecular FormulaC22H30N6O4S
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Purity>98% (HPLC)
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SolubilityWater: 3.5 mg/mL
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SMILESCCCC1=NN(C)C2=C1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(C)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nehra A, et al. World J Urol, 2001, 19(1), 40-45.
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