Cart
sales@molnova.com
VUF11207 fumarate (b)
CAS No. 1378524-41-4
VUF11207 fumarate (b)( VUF-11207 | VUF 11207 )
Catalog No. M11561 CAS No. 1378524-41-4
A potent CXCR7 (ACKR3) agonist with EC50 of 1.6 nM; inducse recruitment of β-arrestin2 and subsequent internalization of CXCR7 in cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVUF11207 fumarate (b)
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent CXCR7 (ACKR3) agonist with EC50 of 1.6 nM; inducse recruitment of β-arrestin2 and subsequent internalization of CXCR7 in cells.
-
DescriptionA potent CXCR7 (ACKR3) agonist with EC50 of 1.6 nM; inducse recruitment of β-arrestin2 and subsequent internalization of CXCR7 in cells.
-
In Vitro——
-
In Vivo——
-
SynonymsVUF-11207 | VUF 11207
-
PathwayGPCR/G Protein
-
TargetChemokine Receptor
-
RecptorChemokine Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1378524-41-4
-
Formula Weight586.66
-
Molecular FormulaC31H39FN2O8
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC(=CC1=CC=CC=C1F)CN(CCC2CCCN2C)C(=O)C3=CC(=C(C(=C3)OC)OC)OC
-
Chemical NameN-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fumarate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wijtmans M, et al. Eur J Med Chem. 2012 May;51:184-92.
molnova catalog
related products
-
BX471 hydrochloride
BX471 is a potent, selective, orally available CCR1 antagonist with Ki of 1 nM for hCCR1, displays 100 times less affinity for rat CCR1.
-
SCH-527123
A potent, selective, orally bioavailable CXCR2/CXCR1 receptor antagonist with Kd of 0.08 and 41 nM for cynomolgus CXCR2 and CXCR1, respectively.
-
AZD-4818
AZD-4818 is a highly potent, selective CCR1 antagonist with pIC50 of 8.6, inhibits chemotaxia of human monocytes to MIP-1α in a concentration-dependent manner.
