VUF11207 fumarate (b)( VUF-11207 | VUF 11207 )

Catalog No. M11561 CAS No. 1378524-41-4

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Product Name

VUF11207 fumarate (b)
Note

Research use only, not for human use.
Brief Description

A potent CXCR7 (ACKR3) agonist with EC50 of 1.6 nM; inducse recruitment of β-arrestin2 and subsequent internalization of CXCR7 in cells.
Description

A potent CXCR7 (ACKR3) agonist with EC50 of 1.6 nM; inducse recruitment of β-arrestin2 and subsequent internalization of CXCR7 in cells.
In Vitro

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In Vivo

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Synonyms

VUF-11207 | VUF 11207
Pathway

GPCR/G Protein
Target

Chemokine Receptor
Recptor

Chemokine Receptor
Research Area

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Indication

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CAS Number

1378524-41-4
Formula Weight

586.66
Molecular Formula

C31H39FN2O8
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(=CC1=CC=CC=C1F)CN(CCC2CCCN2C)C(=O)C3=CC(=C(C(=C3)OC)OC)OC
Chemical Name

N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fumarate

1. Wijtmans M, et al. Eur J Med Chem. 2012 May;51:184-92.

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