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Trilostane
CAS No. 13647-35-3
Trilostane( Desopan | Modrefen | Vetoryl | WIN 24,540 )
Catalog No. M11506 CAS No. 13647-35-3
Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 35 | In Stock |
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| 25MG | 50 | In Stock |
|
| 50MG | 65 | In Stock |
|
| 100MG | 80 | In Stock |
|
| 200MG | 102 | In Stock |
|
| 500MG | 169 | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTrilostane
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NoteResearch use only, not for human use.
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Brief DescriptionTrilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
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DescriptionTrilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
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In Vitro——
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In VivoAnimal Model:Dogs with naturally-occurring pituitary-dependent hyperadrenocorticism (PDH)Dosage:5.3-50 mg/kg Administration:Oral administration; 5.3-50 mg/kg, once daily for 3 months Result:Effectively achieved endocrine control with safe effects and free of side-effects.
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SynonymsDesopan | Modrefen | Vetoryl | WIN 24,540
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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Recptor3 β-hydroxysteroid dehydrogenase
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Research AreaEndocrinology
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Indication——
Chemical Information
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CAS Number13647-35-3
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Formula Weight329.43
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Molecular FormulaC20H27NO3
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Purity>98% (HPLC)
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SolubilityDMSO: 65 mg/mL (197.31 mM)
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SMILESN#CC1=C(O)[C@@]2([H])O[C@@]23[C@]([C@@]4([H])CC[C@@]5(C)[C@](CC[C@@H]5O)([H])[C@]4([H])CC3)(C)C1
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Chemical Name(1aR,4aR,4bS,6aS,7S,9aS,9bS,11aS)-2,7-dihydroxy-4a,6a-dimethyl-1a,4,4a,4b,5,6,6a,7,8,9,9a,9b,10,11-tetradecahydrocyclopenta[7,8]phenanthro[1,10a-b]oxirene-3-carbonitrile.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Puddefoot JR, et al. Expert Opin PharmacOthers. 2006 Dec;7(17):2413-9.
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