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AGI-5198
CAS No. 1355326-35-0
AGI-5198 ( (IDH-C35) )
Catalog No. M11453 CAS No. 1355326-35-0
AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 32 | In Stock |
|
| 10MG | 29 | In Stock |
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| 25MG | 37 | In Stock |
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| 50MG | 43 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAGI-5198
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NoteResearch use only, not for human use.
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Brief DescriptionAGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM.
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DescriptionAGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM.
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In Vitro——
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In Vivo——
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Synonyms(IDH-C35)
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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RecptorR132C-IDH1| R132H-IDH1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1355326-35-0
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Formula Weight462.57
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Molecular FormulaC27H31FN4O2
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Purity>98% (HPLC)
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SolubilityEthanol: 14 mg/mL (30.26 mM); DMSO: 24 mg/mL (51.88 mM)
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SMILESO=C(NC1CCCCC1)C(N(C2=CC=CC(F)=C2)C(CN3C=CN=C3C)=O)C4=CC=CC=C4C
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Chemical NameN-cyclohexyl-2-(N-(3-fluorophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido)-2-(o-tolyl)acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rohle D, et al. Science, 2013, 340(6132), 626-630.
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