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Home - Products - Metabolic Enzyme/Protease - 11β-HSD - BI 187004

BI 187004

CAS No. 1303515-32-3

BI 187004( BI187004 | VTP-34072 )

Catalog No. M11216 CAS No. 1303515-32-3

BI 187004 (VTP-34072) is a novel potent, selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor intended to treat type 2 diabetes mellitus (T2D).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 202 In Stock
5MG 188 In Stock
10MG 353 In Stock
25MG 652 In Stock
50MG 909 In Stock
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Biological Information

  • Product Name
    BI 187004
  • Note
    Research use only, not for human use.
  • Brief Description
    BI 187004 (VTP-34072) is a novel potent, selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor intended to treat type 2 diabetes mellitus (T2D).
  • Description
    BI 187004 (VTP-34072) is a novel potent, selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor intended to treat type 2 diabetes mellitus (T2D).Diabetes Phase 2 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BI187004 | VTP-34072
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    11β-HSD
  • Recptor
    11β-HSD
  • Research Area
    Metabolic Disease
  • Indication
    Diabetes

Chemical Information

  • CAS Number
    1303515-32-3
  • Formula Weight
    342.402
  • Molecular Formula
    C21H18N4O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (4aR,9aS)-1-(1H-benzo[d]imidazole-5-carbonyl)-2,3,4,4a,9,9a-hexahydro1H-indeno[2,1-b]pyridine-6-carbonitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Maw HH, et al. Drug Metab Dispos. 2018 Mar 7. pii: dmd.117.079764.
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