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Dermofongin
CAS No. 130-16-5
Dermofongin( —— )
Catalog No. M11211 CAS No. 130-16-5
5-Chloro-8-hydroxyquinoline, also called Cloxiquine, has the efficancy of anti-viral.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameDermofongin
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NoteResearch use only, not for human use.
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Brief Description5-Chloro-8-hydroxyquinoline, also called Cloxiquine, has the efficancy of anti-viral.
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Description5-Chloro-8-hydroxyquinoline, also called Cloxiquine, has the efficancy of anti-viral.(In Vitro):Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis.Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.(In Vivo):Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
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In VitroCloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis.Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.
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In VivoCloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number130-16-5
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Formula Weight179.6
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Molecular FormulaC9H6ClNO
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESOC1=C2N=CC=CC2=C(Cl)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Latosińska JN, et al. J Mol Model. 2011 Jul;17(7):1781-800.
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