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Gingerenone A
CAS No. 128700-97-0
Gingerenone A( AS-HK014 | AS HK014 | ASHK014 | Gingerenone A | Gingerenone-A )
Catalog No. M11170 CAS No. 128700-97-0
A dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
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| 10MG | 39 | In Stock |
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| 25MG | 72 | In Stock |
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| 50MG | 129 | In Stock |
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| 100MG | 222 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGingerenone A
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NoteResearch use only, not for human use.
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Brief DescriptionA dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells.
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DescriptionA dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells; induces apoptosis in cancer cells and suppresses tumor growth in vivo associated with relative phosphorylation levels of JAK2 and S6K1; suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice.
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In Vitro——
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In Vivo——
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SynonymsAS-HK014 | AS HK014 | ASHK014 | Gingerenone A | Gingerenone-A
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PathwayAngiogenesis
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TargetJAK
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RecptorJAK
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Research Area——
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Indication——
Chemical Information
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CAS Number128700-97-0
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Formula Weight356.418
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Molecular FormulaC21H24O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (280.58 mM)
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SMILESO=C(/C=C/CCC1=CC=C(O)C(OC)=C1)CCC2=CC=C(O)C(OC)=C2
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Chemical Name4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Byun S, et al. J Biol Chem. 2015 Sep 25;290(39):23553-62.
2. Kim HJ, et al. J Cell Biochem. 2018 Jan;119(1):260-268.
3. Suk S, et al. Mol Nutr Food Res. 2017 Oct;61(10).
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