Vilaprisan( BAY 1002670 | BAY 10-02670 )

Catalog No. M11088 CAS No. 1262108-14-4

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Product Name

Vilaprisan
Note

Research use only, not for human use.
Brief Description

Vilaprisan (BAY 1002670) is a highly potent and selective progesterone receptor (PR) modulator.
Description

Vilaprisan (BAY 1002670) is a highly potent and selective progesterone receptor (PR) modulator; exhibits marked efficacy in an innovative humanized fibroid disease model, Vilaprisan is a very promising treatment option for uterine fibroids.Other Indication Phase 3 Clinical.
In Vitro

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In Vivo

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Synonyms

BAY 1002670 | BAY 10-02670
Pathway

Nuclear Receptor/Transcription Factor
Target

Progesterone Receptor
Recptor

Progesterone Receptor
Research Area

Other Indications
Indication

Other Disease

CAS Number

1262108-14-4
Formula Weight

544.577
Molecular Formula

C27H29F5O4S
Purity

>98% (HPLC)
Solubility

——
SMILES

C[C@@]12[C@](C(F)(F)C(F)(F)F)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CCC4=C3[C@@H](C5=CC=C(S(=O)(C)=O)C=C5)C2)=O
Chemical Name

(8S,11R,13S,14S,17R)-17-hydroxy-13-methyl-11-(4-(methylsulfonyl)phenyl)-17-(perfluoroethyl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

1. Wagenfeld A, et al. Hum Reprod. 2013 Aug;28(8):2253-64. 2. Schütt B, et al. Hum Reprod. 2016 Aug;31(8):1703-12.

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