Foslinanib
CAS No. 1256037-60-1
Foslinanib( TRX-818 | TRX818 )
Catalog No. M11045 CAS No. 1256037-60-1
Foslinanib (TRX-818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
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| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameFoslinanib
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NoteResearch use only, not for human use.
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Brief DescriptionFoslinanib (TRX-818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities.
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DescriptionFoslinanib (TRX-818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities, induces cancer cell apoptosis and inhibits cancer cell proliferation; also prevents tumor cell VM by blocking the formation of vasculogenic-like tubular structures through an as of yet undetermined mechanism of action.Liver Cancer Phase 2 Clinical
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In Vitro——
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In Vivo——
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SynonymsTRX-818 | TRX818
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaCancer
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IndicationLiver Cancer
Chemical Information
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CAS Number1256037-60-1
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Formula Weight365.253
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Molecular FormulaC16H13FNO6P
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Purity>98% (HPLC)
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Solubility——
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SMILESO=P(O)(OC1=C(OC)C=CC(NC(C2=CC=CC(F)=C2)=C3)=C1C3=O)O
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Chemical Name2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin5-yl dihydrogen phosphate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Cucurbitacin Q1
Cucurbitacin Q1 is identified as the fruit of Cucumis prophetarum and has been shown to be the pure trans component of cucurbitacin Q.
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Chebulic acid
Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity, which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits the formation of AGEs.
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PKC ζ pseudosubstrat...
Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide. Induces mast cell degranulation by a PKC ζ-independent pathway.
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