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SX-576
CAS No. 1240494-14-7
SX-576( SX 576 | SX576 )
Catalog No. M10973 CAS No. 1240494-14-7
A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSX-576
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively.
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DescriptionA potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively; exhibits potent inhibition of neutrophil influx in rat model of pulmonary inflammation.
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In Vitro——
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In Vivo——
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SynonymsSX 576 | SX576
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorChemokine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1240494-14-7
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Formula Weight466.214
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Molecular FormulaC20H15BF4N2O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESB(C1=C(C=C(C=C1)OC(F)(F)F)CSC2=NC=C(C=C2)C(=O)NC3=CC=C(C=C3)F)(O)O
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Chemical Name(2-(((5-((4-fluorophenyl)carbamoyl)pyridin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Maeda DY, et al. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2280-4.
2. Schuler AD, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3793-7.
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