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Neladenoson dalanate hydrochloride
CAS No. 1239235-25-6
Neladenoson dalanate hydrochloride( BAY 10-67197 )
Catalog No. M10960 CAS No. 1239235-25-6
Neladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameNeladenoson dalanate hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionNeladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.
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DescriptionNeladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.Heart Failure Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsBAY 10-67197
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PathwayApoptosis
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TargetAdenosine Receptor
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RecptorAdenosine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1239235-25-6
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Formula Weight752.73
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Molecular FormulaC35H35Cl2N7O4S2
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Purity>98% (HPLC)
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Solubility——
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SMILESC[C@@H](C(OCCOC1=CC=C(C2=C(C#N)C(SCC3=CSC(C4=CC=C(Cl)C=C4)=N3)=NC(N5CCCC5)=C2C#N)C=C1)=O)NC([C@H](C)N)=O.[H]Cl
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Chemical Name2-{4-[2-({[2-(4-chlorophenyl)-1,3-thiazol- 4-yl]methyl}sulfanyl)-3,5-dicyano-6-(pyrrolidin-1-yl)pyridin- 4-yl]phenoxy}ethyl L-alanyl-L-alaninate hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Meibom D, et al. ChemMedChem. 2017 May 22;12(10):728-737.
2. Voors AA, et al. J Clin Pharmacol. 2017 Apr;57(4):440-451.
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