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AP26113
CAS No. 1197958-12-5
AP26113( —— )
Catalog No. M10707 CAS No. 1197958-12-5
AP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 27 | In Stock |
|
| 5MG | 42 | In Stock |
|
| 10MG | 60 | In Stock |
|
| 25MG | 87 | In Stock |
|
| 50MG | 132 | In Stock |
|
| 100MG | 222 | In Stock |
|
| 200MG | 331 | In Stock |
|
| 500MG | 536 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAP26113
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NoteResearch use only, not for human use.
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Brief DescriptionAP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay.
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DescriptionAP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M mutation. Phase 2.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetALK
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RecptorALK| EGFR (C797S/del19)| EGFR (del19)| EGFR (del19)| IGF-1R
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1197958-12-5
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Formula Weight529.01
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Molecular FormulaC26H34ClN6O2P
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Purity>98% (HPLC)
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SolubilityEthanol: 106 mg/mL (200.37 mM); DMSO: 45 mg/mL (85.06 mM)
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SMILESCOC1=C(NC2=NC=C(Cl)C(NC3=CC=CC=C3P(C)(C)=O)=N2)C=CC(=C1)N1CCC(CC1)N(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sen Zhang, et al. Y Research: April 15, 2010; Volume 70, Issue 8, Supplement 1
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