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Home - Products - GPCR/G Protein - 5-HT Receptor - AVN-322 free base

AVN-322 free base

CAS No. 1194574-33-8

AVN-322 free base( AVN 323 free base )

Catalog No. M10683 CAS No. 1194574-33-8

A highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 1026 In Stock
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Biological Information

  • Product Name
    AVN-322 free base
  • Note
    Research use only, not for human use.
  • Brief Description
    A highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia.
  • Description
    A highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia; significantly restores both scopolamine- and MK-801-induced cognitive dysfunction and demonstrates antipsychotic potential.Alzheimer Disease Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AVN 323 free base
  • Pathway
    GPCR/G Protein
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Neurological Disease
  • Indication
    Alzheimer Disease

Chemical Information

  • CAS Number
    1194574-33-8
  • Formula Weight
    357.432
  • Molecular Formula
    C17H19N5O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CNC1=NN2C3=C(CN(CC3)C)C=NC2=C1S(=O)(=O)C4=CC=CC=C4
  • Chemical Name
    N,7-dimethyl-3-(phenylsulfonyl)-6,7,8,9-tetrahydropyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-2-amine hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ivachtchenko AV, et al. Curr Alzheimer Res. 2017;14(3):268-294.
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