Cart
sales@molnova.com
CI-976
CAS No. 114289-47-3
CI-976( PD 128042 )
Catalog No. M10507 CAS No. 114289-47-3
CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 88 | In Stock |
|
| 5MG | 56 | In Stock |
|
| 10MG | 105 | In Stock |
|
| 25MG | 231 | In Stock |
|
| 50MG | 379 | In Stock |
|
| 100MG | 630 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCI-976
-
NoteResearch use only, not for human use.
-
Brief DescriptionCI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.
-
DescriptionCI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM; decreases plasma total cholesterol, very low density lipoprotein (VLDL) cholesterol, LDL cholesterol, apolipoprotein B, liver cholesteryl esters, and VLDL and LDL cholesteryl ester content in rabbits.Atherosclerosis Discontinued.
-
In Vitro——
-
In Vivo——
-
SynonymsPD 128042
-
PathwayOthers
-
TargetOther Targets
-
RecptorOther Targets
-
Research AreaCardiovascular Disease
-
IndicationAtherosclerosis
Chemical Information
-
CAS Number114289-47-3
-
Formula Weight393.568
-
Molecular FormulaC23H39NO4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (254.09 mM)
-
SMILESCCCCCCCCCCC(C)(C)C(=O)NC1=C(C=C(C=C1OC)OC)OC
-
Chemical Name2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Cucurbit[8]uril
Cucurbit[8]uril is a potent, low toxicity and orally active supramolecular inducer of protein heterodimerization. Cucurbit[8]uril induces heterodimerization of methylviologen and naphthalene functionalized proteins. Cucurbit[8]uril can induce energy trans
-
LysoTracker Red
LysoTracker Red (LysoTracker Red DND-99) is a fluorescent probe compound for lysosomal capture, a transport substrate for P-glycoprotein, with a maximum excitation/emission wavelength of 577/590 nm.LysoTracker Red can be used for the long-term tracking of acidic vesicles.
-
Isorhyncophylline
Isorhyncophylline and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hypertensive effect of angiotensin Ⅱ.
