Succinic acid

Research use only, not for human use.

Succinic acid is a water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters.

Succinic acid is a water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent.(In Vitro):Succinic acid is derived from the fermentation of agricultural carbohydrates.(In Vivo):Succinic acid (3, 6 mg/kg; p.o.) increases the percentage of entries into open arms and of time spent on open arms in male mice.Succinic acid (3, 6, 12 mg/kg; i.p.) significant increases in food intake during 5 min, and 40 min after drug administration rectal temperature was measured, succinic acid at a dose of 1.5 mg/kg, inhibited stress-induced hyperthermia.

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Animal Model:Elevated plus-maze test mice modelDosage:3 mg/kg, 6 mg/kgAdministration: Oral gavage (p.o.); Single doseResult:At doses of 3.0 and 6.0 mg/kg significantly increased the percentage of mice that entered the open arm and the percentage of time that the open arm stayed.Animal Model:Food intake mice modelDosage:3 mg/kg, 6 mg/kg, 12 mg/kg Administration: Intraperitoneal injection (i.p.); Single dose Result:Significantly increased the mice's food intake within 5 minutes after administration.Animal Model:Stress-induced hyperthermia test mice model Dosage:1.5 mg/kg, 3 mg/kg, 6 mg/kg Administration:Oral gavage (p.o.); Single dose Result:Inhibited stress-induced hyperthermia at a dose of 1.5 mg/kg.

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Others

Other Targets

Others

Other Indications

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110-15-6

118.09

C4H6O4

>98% (HPLC)

DMSO: 10 mM

C(CC(=O)O)C(=O)O

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(-20℃)

With Ice Pack

≥ 2 years