Plerixafor( JM-3100 | AMD-3100 | SID-791 )

Catalog No. M10387 CAS No. 110078-46-1

Plerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
5MG	30	In Stock
10MG	46	In Stock
25MG	83	In Stock
50MG	128	In Stock
100MG	212	In Stock
200MG	318	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Plerixafor
Note

Research use only, not for human use.
Brief Description

Plerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor.
Description

Plerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml; can produce mesenchymal stem cells and endothelial progenitor cells in mice in combination with VEGF; also is an allosteric agonist of CXCR7.Blood Cancer Approved.
In Vitro

——
In Vivo

——
Synonyms

JM-3100 | AMD-3100 | SID-791
Pathway

GPCR/G Protein
Target

Chemokine Receptor
Recptor

CXCL12|CXCR4
Research Area

Cancer
Indication

Blood cancer

Chemical Information

CAS Number

110078-46-1
Formula Weight

502.782
Molecular Formula

C28H54N8
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

C1(CN2CCNCCCNCCNCCC2)=CC=C(CN3CCNCCCNCCNCCC3)C=C1
Chemical Name

1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Zabel BA, et al. J Immunol. 2009, 183(5), 3204-3211. 2. De Clercq E, et al. Antimicrob Agents Chemother. 1994 Apr;38(4):668-74. 3. Pitchford SC, et al. Cell Stem Cell. 2009 Jan 9;4(1):62-72.

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