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Plerixafor
CAS No. 110078-46-1
Plerixafor( JM-3100 | AMD-3100 | SID-791 )
Catalog No. M10387 CAS No. 110078-46-1
Plerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | In Stock |
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| 10MG | 57 | In Stock |
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| 25MG | 102 | In Stock |
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| 50MG | 161 | In Stock |
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| 100MG | 291 | In Stock |
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| 200MG | 462 | In Stock |
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| 500MG | 736 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePlerixafor
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NoteResearch use only, not for human use.
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Brief DescriptionPlerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor.
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DescriptionPlerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml; can produce mesenchymal stem cells and endothelial progenitor cells in mice in combination with VEGF; also is an allosteric agonist of CXCR7.Blood Cancer Approved.
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In Vitro——
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In Vivo——
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SynonymsJM-3100 | AMD-3100 | SID-791
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorCXCL12|CXCR4
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Research AreaCancer
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IndicationBlood cancer
Chemical Information
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CAS Number110078-46-1
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Formula Weight502.782
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Molecular FormulaC28H54N8
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESC1(CN2CCNCCCNCCNCCC2)=CC=C(CN3CCNCCCNCCNCCC3)C=C1
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Chemical Name1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zabel BA, et al. J Immunol. 2009, 183(5), 3204-3211.
2. De Clercq E, et al. Antimicrob Agents Chemother. 1994 Apr;38(4):668-74.
3. Pitchford SC, et al. Cell Stem Cell. 2009 Jan 9;4(1):62-72.
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