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Home - Products - JAK/STAT Signaling - Pim - Pim1/AKK1-IN-1

Pim1/AKK1-IN-1

CAS No. 1093222-27-5

Pim1/AKK1-IN-1( LKB1/AAK1 dual inhibitor )

Catalog No. M10359 CAS No. 1093222-27-5

A potent, multikinase inhibitor and also inhibits MPSK1 and TNIK.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 202 In Stock
2MG 126 In Stock
5MG 183 In Stock
10MG 277 In Stock
25MG 489 In Stock
50MG 695 In Stock
100MG 977 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Pim1/AKK1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, multikinase inhibitor and also inhibits MPSK1 and TNIK.
  • Description
    A potent, multikinase inhibitor with Kd of 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    LKB1/AAK1 dual inhibitor
  • Pathway
    JAK/STAT Signaling
  • Target
    Pim
  • Recptor
    Pim
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1093222-27-5
  • Formula Weight
    339.3501
  • Molecular Formula
    C20H13N5O
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(C1=CC=CN=C1)NC2=CNC3=NC=C(C4=CC=C(C#N)C=C4)C=C32
  • Chemical Name
    3-Pyridinecarboxamide, N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bamborough P, et al. J Med Chem. 2008 Dec 25;51(24):7898-914.
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