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PF-04531083
CAS No. 1079400-07-9
PF-04531083( PF-4531083 )
Catalog No. M10319 CAS No. 1079400-07-9
PF-04531083 (PF 4531083) is a potent and selective, orally available sodium channel Nav1.8 blocker for treatment of pain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
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| 5MG | 76 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 217 | In Stock |
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| 50MG | 323 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePF-04531083
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NoteResearch use only, not for human use.
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Brief DescriptionPF-04531083 (PF 4531083) is a potent and selective, orally available sodium channel Nav1.8 blocker for treatment of pain.
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DescriptionPF-04531083 (PF 4531083) is a potent and selective, orally available sodium channel Nav1.8 blocker for treatment of pain. Pain Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsPF-4531083
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorSodium Channel
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Research AreaNeurological Disease
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IndicationPain
Chemical Information
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CAS Number1079400-07-9
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Formula Weight357.798
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Molecular FormulaC17H16ClN5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (279.49 mM)
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SMILESCN1C(=CC=N1)C(=O)NC2=NC(=C(C=C2)C3=C(C=CC(=C3)OC)Cl)N
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Chemical NameN-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bagal SK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.
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