Carbendazim

CAS No. 10605-21-7

Carbendazim( Mercarzole | Carbendazole. Code name: FB462 )

Catalog No. M10269 CAS No. 10605-21-7

Carbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote In Stock
200MG 33 In Stock
500MG 58 In Stock
1G 83 In Stock

Biological Information

  • Product Name
    Carbendazim
  • Note
    Research use only, not for human use.
  • Brief Description
    Carbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities.
  • Description
    Carbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities.(In Vitro):Carbendazim (4-60 μM; 24 hours) has no effects on viability of HeLa cells in a CCK-8 assay.(In Vivo):Carbendazim (oral gavage; 100 and 500 mg/kg; once daily in diet; 28 days) induces hepatic lipid metabolism disorder, it results in a significant increase of hepatic lipid accumulation and triglyceride (TG) levels in mice.
  • In Vitro
    ——
  • In Vivo
    Animal Model:6-week-old male ICR miceDosage:100 and 500 mg/kg Administration:Oral gavage; 100 and 500 mg/kg; once daily in diet; 28 days Result:Increased the relative mRNA levels of some key genes related to lipogenesis and TG synthesis.Up-regulated mRNA levels of IL-1b and IL-6 in the liver in mice.Increased the serum concentrations of 2 proinflammatory cytokines IL-1b and IL-6 at 500 mg/kg. However, in the fat tissues, onlyIL-1b in the CBZ-500-treated group increased significantly as compared with the control group.
  • Synonyms
    Mercarzole | Carbendazole. Code name: FB462
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    10605-21-7
  • Formula Weight
    191.19
  • Molecular Formula
    C9H9N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    O=C(OC)NC1=NC2=CC=CC=C2N1
  • Chemical Name
    methyl 1H-benzo[d]imidazol-2-ylcarbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jiang J, et al. Toxicol In Vitro. 2015 Oct;29(7):1473-8
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