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Valbenazine
CAS No. 1025504-45-3
Valbenazine( NBI-98854 )
Catalog No. M10117 CAS No. 1025504-45-3
A novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 116 | In Stock |
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| 2MG | 53 | In Stock |
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| 5MG | 103 | In Stock |
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| 10MG | 170 | In Stock |
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| 25MG | 330 | In Stock |
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| 50MG | 500 | In Stock |
|
| 100MG | 732 | In Stock |
|
| 200MG | 995 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameValbenazine
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NoteResearch use only, not for human use.
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Brief DescriptionA novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.
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DescriptionA novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.Other Indication Phase 3 Clinical(In Vitro):Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with Kis of 110 and 150 nM, respectively. (In Vivo):Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response.
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In Vitro——
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In Vivo——
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SynonymsNBI-98854
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number1025504-45-3
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Formula Weight418.5695
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Molecular FormulaC24H38N2O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1OC(=O)C(C(C)C)N)OC)OC
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Chemical NameL-Valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. O'Brien CF, et al. Mov Disord. 2015 Oct;30(12):1681-7.
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