Desloratadine

CAS No. 100643-71-8

Desloratadine( Descarboethoxyloratadine | NSC 675447 | SCH 34117 )

Catalog No. M10053 CAS No. 100643-71-8

Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
50MG 32 In Stock
100MG 55 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Desloratadine
  • Note
    Research use only, not for human use.
  • Brief Description
    Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.
  • Description
    Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Descarboethoxyloratadine | NSC 675447 | SCH 34117
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    H1 receptor
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    100643-71-8
  • Formula Weight
    310.82
  • Molecular Formula
    C19H19ClN2
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 62 mg/mL (199.47 mM); DMSO: 26 mg/mL (83.64 mM)
  • SMILES
    C1CC2=C(C=CC(=C2)Cl)C(=C3CCNCC3)C4=C1C=CC=N4
  • Chemical Name
    8-chloro-6,11-dihydro-11-(4-piperdinylidene)- 5h-benzo[5,6]cyclohepta[1,2-b]pyridine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Geha RS, et al. J Allergy Clin Immunol, 2001, 107(4), 751-762.
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