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M-31850
CAS No. 281224-40-6
M-31850 ( 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2,2'-(iminodi-2,1-ethanediyl)bis- )
Catalog No. M24195 CAS No. 281224-40-6
M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor(human HexA and human HexB with IC50s of 6.0 μM and 3.1 μM, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 37 | In Stock |
|
| 25MG | 67 | In Stock |
|
| 50MG | 88 | In Stock |
|
| 100MG | 146 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameM-31850
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NoteResearch use only, not for human use.
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Brief DescriptionM-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor(human HexA and human HexB with IC50s of 6.0 μM and 3.1 μM, respectively).
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DescriptionM-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor(human HexA and human HexB with IC50s of 6.0 μM and 3.1 μM, respectively). IT also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM.
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Synonyms1H-Benz[de]isoquinoline-1,3(2H)-dione, 2,2'-(iminodi-2,1-ethanediyl)bis-
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PathwayOthers
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TargetOther Targets
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Recptorβ-hexosaminidase (Hex)
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Research Area——
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Indication——
Chemical Information
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CAS Number281224-40-6
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Formula Weight463.5
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Molecular FormulaC28H21N3O4
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Purity>98% (HPLC)
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SolubilityDMSO:5 mg/mL?(10.79 mM;?ultrasonic and adjust pH to 6 with HCl)
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SMILESC1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCNCCN4C(=O)C5=CC=CC6=C5C(=CC=C6)C4=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Michael B Tropak, et al. High-throughput screening for human lysosomal beta-N-Acetyl hexosaminidase inhibitors acting as pharmacological chaperones. Chem Biol. 2007 Feb;14(2):153-64.
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