LtaS-IN-1
CAS No. 877950-01-1
LtaS-IN-1 ( —— )
Catalog No. M26284 CAS No. 877950-01-1
LtaS-IN-1 is an effective inhibitor of Lipoteichoic acid synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 110 | Get Quote |
|
10MG | 160 | Get Quote |
|
25MG | 282 | Get Quote |
|
50MG | 439 | Get Quote |
|
100MG | 644 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameLtaS-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionLtaS-IN-1 is an effective inhibitor of Lipoteichoic acid synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology.
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DescriptionLtaS-IN-1 is an effective inhibitor of Lipoteichoic acid synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 is against Enterococcus spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 inhibits strain E1630 and E1590 with MIC values of 0.5 μg/mL.(In Vitro):LtaS-IN-1 (20 μM) combines with either ampicillin (20 μg/mL), gentamicin (10 μg/mL), linezolid (5 μg/mL), daptomycin (10 μg/mL+50 μg/mL calcium chloride) or vancomycin (20 μg/mL) can inhibit strains E7128 and E7130 growth by 97-100%, while LtaS-IN-1 alone only gives 73% (strain E7128) and 8% (strain E7130) of growth inhibition, respectively. LtaS-IN-1 (0-100 μM) inhibits strain E745 growth as a concentration-dependent manner. LtaS-IN-1 (10 μM) leads to a 60% reduction in the final OD600 for this strain. Meanwhile, LtaS-IN-1 does not affect E. faecium growth in control group.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorGABA
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Research Area——
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Indication——
Chemical Information
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CAS Number877950-01-1
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Formula Weight427.4
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Molecular FormulaC24H17N3O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(COC(=O)Cc1coc2ccc3ccccc3c12)Nc1nnc(o1)-c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nakao T, et al. Broflanilide: A meta-diamide insecticide with a novel mode of action. Bioorg Med Chem. 2016 Feb 1;24(3):372-7.
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