
Lindleyin
CAS No. 59282-56-3
Lindleyin( —— )
Catalog No. M22052 CAS No. 59282-56-3
Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens.
Purity : >98% (HPLC)






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Biological Information
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Product NameLindleyin
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NoteResearch use only, not for human use.
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Brief DescriptionLindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens.
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DescriptionLindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens.One herbal extract, Rhei rhizoma (rhubarb), acts as an agonist to both ERalpha and ERbeta. The phytochemical Lindleyin, a major component of rhubarb, might contribute to this estrogenic activity through ERalpha and ERbeta. 4-Hydroxytamoxifen, an ER antagonist, completely reversed the estrogenic activity of Lindleyin. Lindleyin binds to ERalpha in vitro, as demonstrated using a fluorescent polarization assay. The in vivo effect of rhubarb extract was studied using a vitellogenin assay system in the freshwater fish, Japanese medaka (Oryzias latipes). There were marked increases in serum vitellogenin levels in male medaka exposed to rhubarb extract.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptorEstrogen Receptor/ERR|Estrogen/progestogen Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number59282-56-3
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Formula Weight478.45
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Molecular FormulaC23H26O11
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (104.50 mM)
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SMILESCC(=O)CCC1=CC=C(O[C@@H]2O[C@H](COC(=O)C3=CC(O)=C(O)C(O)=C3)[C@@H](O)[C@H](O)[C@H]2O)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.The phytochemical lindleyin, isolated from Rhei rhizoma, mediates hormonal effects through estrogen receptors.J Endocrinol. 2002 Nov;175(2):289-96.
molnova catalog



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