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Lificiguat
CAS No. 170632-47-0
Lificiguat ( YC1; YC 1; YC-1; Lificiguat )
Catalog No. M18115 CAS No. 170632-47-0
YC-1 is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | In Stock |
|
| 10MG | 55 | In Stock |
|
| 25MG | 114 | In Stock |
|
| 50MG | 227 | In Stock |
|
| 100MG | 389 | In Stock |
|
| 200MG | 575 | In Stock |
|
| 500MG | 888 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLificiguat
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NoteResearch use only, not for human use.
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Brief DescriptionYC-1 is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha).
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DescriptionLificiguat, also known as YC-1, is a inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha). YC-1 is widely used as a potent inhibitor of HIF-1alpha both in vitro and in vivo, and is also being developed as a novel anticancer drug. YC-1 effectively inhibits tumor invasion and metastasis, and imply that YC-1 is worth while to further develop as a multipurpose anticancer drug.
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SynonymsYC1; YC 1; YC-1; Lificiguat
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PathwayOthers
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TargetOther Targets
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RecptorsGC;HIF-1α
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number170632-47-0
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Formula Weight304.34
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Molecular FormulaC19H16N2O2
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Purity98%
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SolubilityDMSO : ≥ 51 mg/mL; 167.58 mM
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SMILESOCC1=CC=C(C2=NN(CC3=CC=CC=C3)C4=C2C=CC=C4)O1
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Chemical Name5-[1-(phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Martin E,etal.YC-1 activation of human soluble guanylyl cyclase has both heme-dependent and heme-independent components.Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12938-42.
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