Liensinine( Liensinine | )

Catalog No. M18319 CAS No. 2586-96-1

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Datasheet

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HPLC

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Product Name

Liensinine
Note

Research use only, not for human use.
Brief Description

Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.
Description

Liensinine is a novel autophagy/mitophagy inhibitor.
In Vitro

——
In Vivo

Animal Model:KM miceDosage:100 mg/kg, 200 mg/kg Administration:oral gavage, daily, 10 weeks Result:Reduced the gingival index and increased the SOD levels, the CAT, GSH-Px levels and decreased the NO, MDA, and ET levels compared to the control group.Animal Model:Institute of Cancer Research (ICR) mice (male, 20-22 g) Dosage:Administration:5 mg/kg by oral administration; 1 mg/kg by intravenous administration Result:The pharmacokinetic parameters of Liensinine in mice.
Synonyms

Liensinine |
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

CAS Number

2586-96-1
Formula Weight

610.75
Molecular Formula

C37H42N2O6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (81.87 mM)
SMILES

CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)O)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)OC)O)OC
Chemical Name

4-(((R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-2-(((R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)oxy)phenol