Lidamidine
CAS No. 66871-56-5
Lidamidine ( Lidamidina; Lidamidinum )
Catalog No. M27821 CAS No. 66871-56-5
Lidamidine is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle contraction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 393 | Get Quote |
|
10MG | 581 | Get Quote |
|
25MG | 888 | Get Quote |
|
50MG | 1242 | Get Quote |
|
100MG | 1674 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameLidamidine
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NoteResearch use only, not for human use.
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Brief DescriptionLidamidine is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle contraction.
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DescriptionLidamidine is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle contraction.(In Vivo):Fasted male rats were anesthetised and equipped with an intraluminal cannula positioned at the proximal end of a 10 cm fluid-filled segment of the ascending colon (basal pressure, 10 cm H2O). Intraluminal pressure was monitored by a transducer attached to a closed fluid-filled system. All drugs were administered intravenously by slow infusion. A regular pattern of distinct contractile complexes was observed over a 70 min period. These contractions increased intraluminal pressure to 39 +/- 1.2 cm H2O (mean +/- S.E.), occurred at a frequency of 0.3 per min and lasted from 1 to 2.5 min. Inhibition of these contractile patterns was observed with either atropine (0.1 mg/kg) or lidamidine (3.0 mg/kg). A 20 min pretreatment with idazoxan (3.0 mg/kg) antagonized lidamidine's but not atropine's effect. Trimazosin (1 mg/kg) or propranolol (0.3 mg/kg) pretreatment did not antagonize the lidamidine-generated inhibition.
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SynonymsLidamidina; Lidamidinum
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PathwayOthers
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TargetOther Targets
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RecptorH1 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number66871-56-5
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Formula Weight220.3
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Molecular FormulaC11H16N4O
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Purity>98% (HPLC)
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Solubility——
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SMILESCNC(=N)NC(=O)Nc1c(C)cccc1C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Towart R, et al. Investigation of the antihistaminic action of dimethindene maleate (Fenistil) and its optical isomers. Agents Actions Suppl. 1991;33:403-8.
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