
Licarbazepine
CAS No. 29331-92-8
Licarbazepine( Licarbazepine | ?1011-hydroxy-1011 Dihydrocarbamezer )
Catalog No. M21077 CAS No. 29331-92-8
Licarbazepine is the pharmacologically active metabolite of oxcarbazepine a drug indicated for the treatment of partial seizures and bipolar disorders.
Purity : >98% (HPLC)






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50MG | 87 | Get Quote |
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100MG | 110 | Get Quote |
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200MG | 160 | Get Quote |
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Biological Information
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Product NameLicarbazepine
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NoteResearch use only, not for human use.
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Brief DescriptionLicarbazepine is the pharmacologically active metabolite of oxcarbazepine a drug indicated for the treatment of partial seizures and bipolar disorders.
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DescriptionLicarbazepine is the pharmacologically active metabolite of oxcarbazepine a drug indicated for the treatment of partial seizures and bipolar disorders.(In Vivo):Eslicarbazepine acetate (ESL) is an oral pro-drug that is rapidly and extensively metabolized by the liver via a hydrolytic first-pass metabolism into S-Licarbazepine, the biologically active drug. The plasma level of the prodrug remains below quantification.ESL is a potent antiepileptic agent with a spectrum of action essentially limited to partial-onset and generalized tonic-clonic seizures. Its main mechanism of action is by blocking the voltage-gated sodium channel. ESL works by blocking the voltage-gated sodium channel, which play an essential role in the generation and propagation of the epileptic discharge. ESL is well absorbed after oral administration with a bio-availability about 16% higher than that observed after an equivalent dose of Oxcarbazepine (OXC).
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In Vitro——
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In VivoEslicarbazepine acetate (ESL) is an oral pro-drug that is rapidly and extensively metabolized by the liver via a hydrolytic first-pass metabolism into S-Licarbazepine, the biologically active drug. The plasma level of the prodrug remains below quantification. ESL is a potent antiepileptic agent with a spectrum of action essentially limited to partial-onset and generalized tonic-clonic seizures. Its main mechanism of action is by blocking the voltage-gated sodium channel. ESL works by blocking the voltage-gated sodium channel, which play an essential role in the generation and propagation of the epileptic discharge.?ESL is well absorbed after oral administration with a bio-availability about 16% higher than that observed after an equivalent dose of Oxcarbazepine (OXC).
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SynonymsLicarbazepine | ?1011-hydroxy-1011 Dihydrocarbamezer
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaNeurological Disease
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IndicationBipolar Disorder
Chemical Information
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CAS Number29331-92-8
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Formula Weight254.28
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Molecular FormulaC15H14N2O2
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Purity>98% (HPLC)
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SolubilityDMSO:3mg/ml(11.7mM)
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SMILESNC(=O)N1c2ccccc2CC(O)c2ccccc21
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Chemical Name10-hydroxy-1011-dihydro-5H-dibenzo[bf]azepine-5-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference



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Peroxydehydrotumulos...
5alpha,8alpha-Peroxydehydrotumulosic acid exhibits inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells.
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L-Aspartic acid
Aspartic Acid is a non-essential amino acid in humans, Aspartic Acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycles.
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X-press Tag Peptide
X-press Tag is an N-terminal leader peptide; this N-terminal peptide contains a polyhistidine sequence, the Xpress epitope (part of bacteriophage T7 gene 10 protein) and an enterokinase cleavage site. Anti-Xpress antibodies recognize the Xpress epitope sequence found in this leader peptide.