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Levonorgestrel

CAS No. 797-63-7

Levonorgestrel( Levonorgestrel, Norgestrel, Microval, Postinor, Mirena, Plan B )

Catalog No. M15986 CAS No. 797-63-7

Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Levonorgestrel
  • Note
    Research use only, not for human use.
  • Brief Description
    Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives.
  • Description
    Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives.
  • In Vitro
    Western Blot Analysis Cell Line:Uterine leiomyoma cells Concentration:5 mg/mL; 10mg/mL; 20 mg/mL Incubation Time:Result:Inhibited Bcl-2 and survivin expression at high concentrations (10 mg/mL and 20 mg/mL). Significantly increased the phosphorylation of P38 phosphorylation and increased Caspase-3 expression at high concentrations (10 mg/mL and 20 mg/mL).
  • In Vivo
    Animal Model:Apodemus agrarius modelDosage:1 mg/kg Administration:Intragastric administration (i.g.), Once daily for three days Result:Damaged the sperm ducts, reduced sperm production in combination with quinestrol.Reduced population density in the field in combination with quinestrol.
  • Synonyms
    Levonorgestrel, Norgestrel, Microval, Postinor, Mirena, Plan B
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    ER| SRD5A1
  • Research Area
    Endocrinology
  • Indication
    ——

Chemical Information

  • CAS Number
    797-63-7
  • Formula Weight
    312.45
  • Molecular Formula
    C21H28O2
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 2 mg/mL (6.4 mM); DMSO: 45 mg/mL (144.02 mM)
  • SMILES
    CC[C@]12CC[C@H]3[C@@H](CCC4=CC(CC[C@H]34)=O)[C@@H]1CC[C@@]2(O)C#C
  • Chemical Name
    (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Maruo T, et al. Co ntraception. 2007 Jun; 75(6 Suppl):S99-103.
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