Levodopa( 3,4-Dihydroxyphenylalanine | Levodopa )

Catalog No. M15230 CAS No. 59-92-7

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Levodopa
Note

Research use only, not for human use.
Brief Description

L-DOPA is a natural form of DOPA used in the treatment of Parkinson disease.
Description

L-DOPA is a natural form of DOPA used in the treatment of Parkinson disease. L-DOPA is the precursor of dopamine and product of tyrosine hydroxylase.
In Vitro

——
In Vivo

Animal Model:7-week-old C57BL/6J mice Dosage:20 mg/kg Administration:Orally Result:Reduced Rotenone-induced motor dysfunction.Animal Model:Sprague-Dawley rats (male 100-150 g) Dosage:10, 30, 50, 70, and 100 mg/kg Administration:Orally Result:Reverses tactile, cold and heat allodynia in neuropathic rat without any side effect.
Synonyms

3,4-Dihydroxyphenylalanine | Levodopa
Pathway

GPCR/G Protein
Target

Dopamine Receptor
Recptor

Dopamine
Research Area

Neurological Disease
Indication

——

CAS Number

59-92-7
Formula Weight

197.19
Molecular Formula

C9H11NO4
Purity

>98% (HPLC)
Solubility

Ethanol: <1 mg/mL (<1 mM); Water: <1 mg/mL (<1 mM); DMSO: <1 mg/mL (<1 mM)
SMILES

C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O
Chemical Name

——

1. Onofrj M, et al. Expert Opin Investig Drugs. 2008 Jul; 17(7):1115-25.

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