
Lawsone
CAS No. 83-72-7
Lawsone( Lawsone )
Catalog No. M19160 CAS No. 83-72-7
Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).
Purity : >98% (HPLC)






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Biological Information
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Product NameLawsone
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NoteResearch use only, not for human use.
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Brief DescriptionLawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).
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DescriptionLawsone is a molluscacide from leaves of Lawsonia inermis L. topical sunscreening agent; powdered leaves of Lawsonia inermis(Lythraceae) used as brown hair dye.
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In VitroCell Proliferation Assay Cell Line:DLD-1, MRC-5 Concentration:0.5, 1, 1.5, 2 mg/mL Incubation Time:24-96 h Result:Demonstrated significant suppression at concentration 2 mg/ml on DLD-1 cells and exhibited no suppression on normal fibroblast MRC-5 cells.Western Blot Analysis Cell Line:DLD-1 Concentration:0.5, 1, 1.5, 2 mg/mL Incubation Time:48 h Result:Decreased the level of both proteins cyclin B1 and cdk1. Exhibited a dose-dependent effect on translocation of p65 of cytosol to the nucleus.
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In VivoAnimal Model:Female rat model (10-11- week-old)Dosage:62.5, 125, 250, 500, 750 μmol/kg/day Administration:p.o.Result:Increased the levels of ALT、AST、GLDH、LDH、HBDH、urea and creatinine at a dose of 500 or 750 μmol/kg/day.Animal Model:Rat model of colon cancer Dosage: 200 mg/mL Administration:p.o.Result:Reduced the tumor diameters and decreased multiplicity of these adenomas.
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SynonymsLawsone
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number83-72-7
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Formula Weight174.16
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Molecular FormulaC10H6O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (574.22 mM)
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SMILESc1ccc2c(c1)C(=O)C(=CC2=O)O
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Chemical Name1,4-Naphthalenedione, 2-hydroxy-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Munt DJ, et al. AAPS PharmSciTech. 2015 Dec;16(6):1425-33.
molnova catalog



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