Lats-IN-1 ( —— )

Catalog No. M23576 CAS No. 1424635-83-5

Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	133	In Stock
10MG	209	In Stock
25MG	415	In Stock
50MG	536	In Stock
100MG	763	In Stock
200MG	1053	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Lats-IN-1
Note

Research use only, not for human use.
Brief Description

Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.
Description

Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Lats1;Lats2
Research Area

——
Indication

——

Chemical Information

CAS Number

1424635-83-5
Formula Weight

334.4
Molecular Formula

C18H14N4OS
Purity

>98% (HPLC)
Solubility

DMSO:83.33 mg/mL (249.20 mM; Need ultrasonic)
SMILES

O=C(C1=CNC2=NC=CC=C12)/N=C(SC=C3)/N3CC4=CC=CC=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Nathaniel Kastan, et al. Small-molecule inhibition of Lats kinases promotes Yap-dependent proliferation in postmitotic mammalian tissues. bioRxiv 2020.02.11.944157.

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