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Laquinimod
CAS No. 248281-84-7
Laquinimod ( ABR-215062;ABR 215062;ABR215062 )
Catalog No. M13726 CAS No. 248281-84-7
Laquinimod (ABR-215062) is an immunoregulator derived from Linomide, has been shown to completely inhibit the development of murine acute experimental autoimmune encephalomyelitis (EAE).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | In Stock |
|
| 10MG | 55 | In Stock |
|
| 25MG | 68 | In Stock |
|
| 50MG | 88 | In Stock |
|
| 100MG | 135 | In Stock |
|
| 500MG | 332 | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLaquinimod
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NoteResearch use only, not for human use.
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Brief DescriptionLaquinimod (ABR-215062) is an immunoregulator derived from Linomide, has been shown to completely inhibit the development of murine acute experimental autoimmune encephalomyelitis (EAE).
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DescriptionLaquinimod (ABR-215062) is an immunoregulator derived from Linomide, has been shown to completely inhibit the development of murine acute experimental autoimmune encephalomyelitis (EAE); dose-dependently reduces the incidence of EAN, ameliorated clinical signs and inhibited P0 peptide 180-199-specific T cell responses as well as also the decreased inflammation and demyelination in the peripheral nerves; shows improved potency and superior toxicological profile compared to the lead compound Roquinimex (Linomide).Multiple Sclerosis Approved
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SynonymsABR-215062;ABR 215062;ABR215062
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaInflammation/Immunology
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IndicationMultiple Sclerosis
Chemical Information
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CAS Number248281-84-7
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Formula Weight356.80
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Molecular FormulaC19H17ClN2O3
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(C1=C(O)C2=C(N(C)C1=O)C=CC=C2Cl)N(CC)C3=CC=CC=C3
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Chemical Name3-Quinolinecarboxamide, 5-chloro-N-ethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zou LP, et al. Neuropharmacology. 2002 Apr;42(5):731-9.
2. Brunmark C, et al. J Neuroimmunol. 2002 Sep;130(1-2):163-72.
3. Jnsson S, et al. J Med Chem. 2004 Apr 8;47(8):2075-88.
4. Polman C, et al. Neurology. 2005 Mar 22;64(6):987-91.
2. Brunmark C, et al. J Neuroimmunol. 2002 Sep;130(1-2):163-72.
3. Jnsson S, et al. J Med Chem. 2004 Apr 8;47(8):2075-88.
4. Polman C, et al. Neurology. 2005 Mar 22;64(6):987-91.
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