Lapachol

CAS No. 84-79-7

Lapachol( Lapachol | NSC-11905 | Tecomin | Bethabarra wood )

Catalog No. M19177 CAS No. 84-79-7

Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 37 In Stock
50MG 74 In Stock
100MG 112 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Lapachol
  • Note
    Research use only, not for human use.
  • Brief Description
    Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties.
  • Description
    Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.
  • In Vitro
    Cell Proliferation Assay Cell Line:Murine CD4 T cells Concentration:10, 30, 100 μM Incubation Time:4 days Result:Inhibited the proliferation of murine CD4 T cells in a dose-dependent manner.
  • In Vivo
    Animal Model:Male DBA1/J mice (10-12 weeks old) with collagen-induced arthritis (CIA) modelsDosage:3 mg/kg and 10 mg/kg Administration:Orally; once a day for 4 weeks Result:Markedly attenuated the severity of arthritis in CIA mice at both doses. Markedly reduced all histopathological features of arthritis severity.
  • Synonyms
    Lapachol | NSC-11905 | Tecomin | Bethabarra wood
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    others
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    84-79-7
  • Formula Weight
    242.27
  • Molecular Formula
    C15H14O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 66.67 mg/mL (275.19 mM)
  • SMILES
    CC(C)=CCC1=C(O)C(=O)c2ccccc2C1=O
  • Chemical Name
    2-hydroxy-3-(3-methylbut-2-en-1-yl)naphthalene-1,4-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Costa WF,et al. Lapachol as an epithelial tumor inhibitor agent in Drosophila melanogaster heterozygote for tumor suppressor gene wts.Genet Mol Res. 2011 Dec 22;10(4):3236-45.
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