Cart
sales@molnova.com
Lactisole
CAS No. 150436-68-3
Lactisole( 2-(4-Methoxyphenoxy)propanoic acid )
Catalog No. M28055 CAS No. 150436-68-3
Lactisole is an inhibitor of the glucose-sensing receptor.
Lactisole is an inhibitor of the glucose-sensing receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 32 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameLactisole
-
NoteResearch use only, not for human use.
-
Brief DescriptionLactisole is an inhibitor of the glucose-sensing receptor.
-
DescriptionLactisole is an inhibitor of the glucose-sensing receptor.(In Vitro):In MIN6 cells, in a dose-dependent manner, lactisole inhibited insulin secretion induced by sweeteners, acesulfame-K, sucralose and glycyrrhizin. The IC50 was ～4 mmol/l. Lactisole attenuated the elevation of cytoplasmic Ca2+ concentration ([Ca2+]c) evoked by sucralose and acesulfame-K but did not affect the elevation of intracellular cAMP concentration ([cAMP]c) induced by these sweeteners. Lactisole also inhibited the action of glucose in MIN6 cells. Thus, lactisole significantly reduced elevations of intracellular [NADH] and intracellular [ATP] induced by glucose, and also inhibited glucose-induced insulin secretion.
-
In Vitro
-
In Vivo
-
Synonyms2-(4-Methoxyphenoxy)propanoic acid
-
PathwayOthers
-
TargetOther Targets
-
RecptorApoptosis|PKG
-
Research Area
-
Indication
Chemical Information
-
CAS Number150436-68-3
-
Formula Weight218.184
-
Molecular FormulaC10H11NaO4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (572.92 mM)
-
SMILES[Na+].COc1ccc(OC(C)C([O-])=O)cc1
-
Chemical Name
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Singh T, et al. Nitric oxide donor exisulind is an effective inhibitor of murine photocarcinogenesis. Photochem Photobiol. 2012 Sep-Oct;88(5):1141-8.
molnova catalog
related products
-
O-Acetyl-L-serine hy...
O-Acetylserine (OASS) is an acylated amino acid derivative. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. Its presence in humans arises from either microbial metabolism in the gut or through consumption of foods containing OASS.
-
Catechin 7,3-di-O-be...
The herbs of Spiraea hypericifolia L.
-
SPR741
SPR741, formerly NAB741 (12), is a cationic peptide derived from polymyxin B and is one such potentiator molecule that is under development for the treatment of serious Gram-negative bacterial infections.
