LY2979165( mGlu2 agonist )

Catalog No. M26747 CAS No. 1311385-32-6

LY2979165 is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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25MG	420	In Stock
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Biological Information

Product Name

LY2979165
Note

Research use only, not for human use.
Brief Description

LY2979165 is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.
Description

LY2979165 is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.(In Vivo):LY2979165 reduces BOLD signal and increases plasma levels of 2812223 in vivo.
In Vitro

——
In Vivo

LY2979165 attenuated the ketamine-evoked BOLD phMRI signal in vivo.
Synonyms

mGlu2 agonist
Pathway

Neuroscience
Target

GluR
Recptor

NK1| NK3
Research Area

——
Indication

——

Chemical Information

CAS Number

1311385-32-6
Formula Weight

390.42
Molecular Formula

C13H22N6O6S
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : ≥ 50 mg/mL (128.07 mM)D)
SMILES

N.O.C[C@H](N)C(=O)N[C@]1(C[C@@H](Sc2ncn[nH]2)[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Pawsey S, et al. Elinzanetant (NT-814), a Neurokinin 1,3 Receptor Antagonist, Reduces Estradiol and Progesterone in Healthy Women. J Clin Endocrinol Metab. 2021 Jul 13;106(8):e3221-e3234.

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