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LY2881835
CAS No. 1292290-38-0
LY2881835( —— )
Catalog No. M34327 CAS No. 1292290-38-0
LY2881835 is a potent and selective GPR40 agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 445 | Get Quote |
|
| 5MG | 686 | Get Quote |
|
| 10MG | 938 | Get Quote |
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| 25MG | 1398 | Get Quote |
|
| 50MG | 1822 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLY2881835
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NoteResearch use only, not for human use.
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Brief DescriptionLY2881835 is a potent and selective GPR40 agonist.
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DescriptionLY2881835 is a potent and selective agonist of G protein-coupled receptor 40 (GPR40). LY2881835 has efficacious and durable dose-dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion. LY2881835 has the potential for the research of type 2 diabetes mellitus. LY2881835 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetGPR
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RecptorGPR
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Research Area——
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Indication——
Chemical Information
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CAS Number1292290-38-0
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Formula Weight491.62
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Molecular FormulaC33H33NO3
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Purity>98% (HPLC)
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Solubility——
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SMILESC(N1CCC2(C=3C(C=C2)=CC=CC3)CC1)C4=CC=C(COC5=CC=C([C@H](CC(O)=O)C#CC)C=C5)C=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hamdouchi C, et al. The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470). J Med Chem. 2016;59(24):10891-10916.?
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