Cart
sales@molnova.com
LTX-315
CAS No. 1345407-05-7
LTX-315( Oncopore )
Catalog No. M11383 CAS No. 1345407-05-7
LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 79 | In Stock |
|
| 5MG | 113 | In Stock |
|
| 10MG | 194 | In Stock |
|
| 25MG | 354 | In Stock |
|
| 50MG | 527 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLTX-315
-
NoteResearch use only, not for human use.
-
Brief DescriptionLTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes.
-
DescriptionLTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis; triggers immunogenic cell death, induces cell death and DAMP release by mitochondria distortion in human melanoma cells.Breast Cancer Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsOncopore
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research AreaCancer
-
IndicationBreast Cancer
Chemical Information
-
CAS Number1345407-05-7
-
Formula Weight1439.823
-
Molecular FormulaC78H106N18O9
-
Purity>98% (HPLC)
-
SolubilityEthanol: 100 mg/mL (69.45 mM); DMSO: <1 mg/mL; Water: 100 mg/mL (69.45 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESNCCCC[C@@H](C(N)=O)NC([C@H](C(C1=CC=CC=C1)C2=CC=CC=C2)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CC5=CNC6=C5C=CC=C6)NC([C@H](CC7=CNC8=C7C=CC=C8)NC([C@H](CCCCN)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O
-
Chemical NameL-Lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-β-phenyl-L-phenylalanyl-L-lysinamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Haug BE, et al. J Med Chem. 2016 Apr 14;59(7):2918-27.
2. Forveille S, et al. Cell Cycle. 2015;14(21):3506-12.
3. Zhou H, et al. Oncotarget. 2015 Sep 29;6(29):26599-614.
4. Eike LM, et al. Oncotarget. 2015 Oct 27;6(33):34910-23.
molnova catalog
related products
-
Aloe-emodin-3-(hydro...
Aloe-emodin-3-(hydroxymethyl)-O-beta-D-glucopyranoside is a natural product.
-
Porcine dynorphin A(...
Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.
-
9-Methymyrrhone
9-Methymyrrhone is a natural product.
