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LTX-315
CAS No. 1345407-05-7
LTX-315 ( Oncopore )
Catalog No. M11383 CAS No. 1345407-05-7
LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 79 | In Stock |
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| 5MG | 113 | In Stock |
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| 10MG | 194 | In Stock |
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| 25MG | 354 | In Stock |
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| 50MG | 527 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLTX-315
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NoteResearch use only, not for human use.
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Brief DescriptionLTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes.
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DescriptionLTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis; triggers immunogenic cell death, induces cell death and DAMP release by mitochondria distortion in human melanoma cells.Breast Cancer Phase 2 Clinical
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SynonymsOncopore
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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IndicationBreast Cancer
Chemical Information
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CAS Number1345407-05-7
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Formula Weight1439.82
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Molecular FormulaC78H106N18O9
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Purity>98% (HPLC)
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SolubilityEthanol: 100 mg/mL (69.45 mM); DMSO: <1 mg/mL; Water: 100 mg/mL (69.45 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESNCCCC[C@@H](C(N)=O)NC([C@H](C(C1=CC=CC=C1)C2=CC=CC=C2)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CC5=CNC6=C5C=CC=C6)NC([C@H](CC7=CNC8=C7C=CC=C8)NC([C@H](CCCCN)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O
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Chemical NameL-Lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-β-phenyl-L-phenylalanyl-L-lysinamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Haug BE, et al. J Med Chem. 2016 Apr 14;59(7):2918-27.
2. Forveille S, et al. Cell Cycle. 2015;14(21):3506-12.
3. Zhou H, et al. Oncotarget. 2015 Sep 29;6(29):26599-614.
4. Eike LM, et al. Oncotarget. 2015 Oct 27;6(33):34910-23.
2. Forveille S, et al. Cell Cycle. 2015;14(21):3506-12.
3. Zhou H, et al. Oncotarget. 2015 Sep 29;6(29):26599-614.
4. Eike LM, et al. Oncotarget. 2015 Oct 27;6(33):34910-23.
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