Cart
sales@molnova.com
LN-1-255
CAS No. 247115-03-3
LN-1-255( LN 1-255 | LN1255 )
Catalog No. M13722 CAS No. 247115-03-3
LN-1-255 is a 6-alkylidene-2'-substituted penicillin sulfone that acts as an effective beta-lactamase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameLN-1-255
-
NoteResearch use only, not for human use.
-
Brief DescriptionLN-1-255 is a 6-alkylidene-2'-substituted penicillin sulfone that acts as an effective beta-lactamase inhibitor.
-
DescriptionLN-1-255 is a 6-alkylidene-2'-substituted penicillin sulfone that acts as an effective beta-lactamase inhibitor; inhibits SHV-1 and SHV-2 beta-lactamases with Ki of 110 nM and 100 nM, significantly enhances the activity of ceftazidime and cefpirome against extended-spectrum cephalosporin and Sme-1 containing carbapenem-resistant clinical strains; also inhibits the class D carbapenemase OXA-48 with IC50 of 3 nM, an important emerging mechanism of antibiotic resistance.
-
In Vitro——
-
In Vivo——
-
SynonymsLN 1-255 | LN1255
-
PathwayGPCR/G Protein
-
TargetAntibacterial
-
RecptorAntibacterial
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number247115-03-3
-
Formula Weight510.449
-
Molecular FormulaC22H19N2NaO9S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-[[[(3,4-dihydroxyphenyl)acetyl]oxy]methyl]-3-methyl-7-oxo-6-(2-pyridinylmethylene)-, 4,4-dioxide, monosodium salt, (2S,3R,5R,6Z)- (9CI)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Pattanaik P, et al. J Biol Chem. 2009 Jan 9;284(2):945-53.
2. Vallejo JA, et al. J Antimicrob Chemother. 2016 Aug;71(8):2171-80.
3. Vázquez-Ucha JC, et al. Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01172-17.
molnova catalog
related products
-
Monoctanoin
Monoctanoin has antibacterial activity against Staphylococcus aureus and Escherichia coli.
-
N-Acetyl-D-mannosami...
N-Acetylmannosamine is a drug potentially for the treatment of hereditary inclusion body myopathy.
-
Hemipyocyanine
Hemipyocyanine is the virulence factor of Gram-negative, aerobic rod bacterium Pseudomonas aeruginosa. Hemipyocyanine is an α-Amylase inhibitor.
