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LMTK3-IN-1
CAS No. 2764850-23-7
LMTK3-IN-1( —— )
Catalog No. M36996 CAS No. 2764850-23-7
Lmtk3-in-1 is a potent ATP-competitive lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM) inhibitor that degrades LMTK3 through the ubiquitin proteasome pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 73 | Get Quote |
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| 5MG | 107 | Get Quote |
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| 10MG | 169 | Get Quote |
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| 25MG | 273 | Get Quote |
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| 50MG | 417 | Get Quote |
|
| 100MG | 590 | Get Quote |
|
| 500MG | 1224 | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLMTK3-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionLmtk3-in-1 is a potent ATP-competitive lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM) inhibitor that degrades LMTK3 through the ubiquitin proteasome pathway.
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DescriptionLMTK3-IN-1 (compound C28) is an ATP-competitive inhibitor of lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM)，that acts by degrading LMTK3 via the ubiquitin-proteasome pathway. LMTK3-IN-1 shows anticancer activity in a variety of cancer cell lines and in vivo BC mouse models. LMTK3-IN-1 induces apoptosis in BC cell lines at 10-20 μM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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Targetc-Met/HGFR
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Recptorc-Met/HGFR
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Research Area——
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Indication——
Chemical Information
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CAS Number2764850-23-7
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Formula Weight356.3
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Molecular FormulaC18H11F3N4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 5 mg/mL (14.03 mM; Ultrasonic (<60°C)
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SMILESFC(F)(F)OC1=CC=CC(=C1)C2=CN=C3C=CC(=NN32)C=4C=CN=CC4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Agnarelli A, et al. The Inhibitory Properties of a Novel, Selective LMTK3 Kinase Inhibitor. Int J Mol Sci. 2023 Jan 3;24(1):865.?
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