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LML-134
CAS No. 1542135-76-1
LML-134 ( —— )
Catalog No. M21945 CAS No. 1542135-76-1
LML-134 is an inverse agonist of Histamine 3 receptor (H3R)(hH3R cAMP and hH3R bdg with Kis of 0.3 nM and 12 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 174 | Get Quote |
|
| 5MG | 258 | Get Quote |
|
| 10MG | 410 | Get Quote |
|
| 25MG | 678 | Get Quote |
|
| 50MG | 954 | Get Quote |
|
| 100MG | 1287 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLML-134
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NoteResearch use only, not for human use.
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Brief DescriptionLML-134 is an inverse agonist of Histamine 3 receptor (H3R)(hH3R cAMP and hH3R bdg with Kis of 0.3 nM and 12 nM).
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DescriptionLML-134 is an inverse agonist of Histamine 3 receptor (H3R)(hH3R cAMP and hH3R bdg with Kis of 0.3 nM and 12 nM).
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Synonyms——
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorH3 receptor
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Research AreaNervous system
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IndicationCircadian Rhythm Disorders
Chemical Information
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CAS Number1542135-76-1
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Formula Weight375.47
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Molecular FormulaC19H29N5O3
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Purity>98% (HPLC)
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SolubilityDMSO:7.5 mg/ml(19.97 mM; Need ultrasonic)
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SMILESCn1nc(ccc1=O)N1CCC(CC1)OC(=O)N1CCN(CC1)C1CCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Troxler T, et al. The Discovery of LML134, a Histamine H3 Receptor Inverse Agonist for the Clinical Treatment of Excessive Sleep Disorders. ChemMedChem. 2019 Jul 3;14(13):1238-1247.
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