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LM10
CAS No. 1316695-35-8
LM10 ( LM10; LM 10; LM-10 )
Catalog No. M17944 CAS No. 1316695-35-8
Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 27 | In Stock |
|
| 10MG | 42 | In Stock |
|
| 25MG | 87 | In Stock |
|
| 50MG | 156 | In Stock |
|
| 100MG | 302 | In Stock |
|
| 200MG | 474 | In Stock |
|
| 500MG | 758 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLM10
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NoteResearch use only, not for human use.
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Brief DescriptionSelective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively).
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DescriptionLM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). LM10 exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. LM10 reduces growth of TDO-expressing P815 mastocytoma tumors in mice.
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SynonymsLM10; LM 10; LM-10
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PathwayOthers
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TargetOther Targets
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RecptorTDO
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number1316695-35-8
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Formula Weight229.22
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Molecular FormulaC11H8FN5
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Purity98%
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Solubility——
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SMILESFc2cc3ncc(/C=C/c1nnnn1)c3cc2
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Chemical Name6-fluoro-3-[(E)-2-(1H-1,2,3,4-tetrazol-5-yl)ethenyl]-1H-indole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pilotte L,etal.Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase.Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2497-502.
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