LGD-4033

CAS No. 1165910-22-4

LGD-4033( LGD 4033 | LGD4033 | VK-5211 )

Catalog No. M10567 CAS No. 1165910-22-4

A novel nonsteroidal, oral selective androgen receptor modulator (SARM), binds androgen receptor with high affinity (Ki=1 nM) and selectivity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    LGD-4033
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel nonsteroidal, oral selective androgen receptor modulator (SARM), binds androgen receptor with high affinity (Ki=1 nM) and selectivity.
  • Description
    A novel nonsteroidal, oral selective androgen receptor modulator (SARM), binds androgen receptor with high affinity (Ki=1 nM) and selectivity; has favorable pharmacokinetic profile, and increases lean body mass even during this short period without change in prostate-specific antigen.Other Indication Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    LGD 4033 | LGD4033 | VK-5211
  • Pathway
    Endocrinology/Hormones
  • Target
    Androgen Receptor (AR)
  • Recptor
    Androgen Receptor (AR)
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    1165910-22-4
  • Formula Weight
    338.25
  • Molecular Formula
    C14H12F6N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 100 mg/mL (295.64 mM)
  • SMILES
    N#CC1=CC=C(N2[C@@H]([C@@H](O)C(F)(F)F)CCC2)C=C1C(F)(F)F
  • Chemical Name
    4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-(trifluoromethyl)benzonitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Basaria S, et al. J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):87-95.
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