Home - Products - Chromatin/Epigenetic - HMTase - LEM-14-1189

LEM-14-1189

CAS No.

LEM-14-1189 ( —— )

Catalog No. M17069 CAS No.

LEM-14-1189 is a LEM-14 derivative that differentially inhibits the NSDs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
100MG	Get Quote	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

LEM-14-1189
Note

Research use only, not for human use.
Brief Description

LEM-14-1189 is a LEM-14 derivative that differentially inhibits the NSDs.
Description

LEM-14-1189 is a LEM-14 derivative that differentially inhibits the NSDs with in vitro IC50 of 418μM (NSD1), IC50 of 111μM (NSD2) and IC50 of 60μM (NSD3).
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

HMTase
Recptor

HMTase
Research Area

——
Indication

——

Chemical Information

CAS Number

--
Formula Weight

682.81
Molecular Formula

C35H34N6O5S2
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

N-(3-(bis((4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)methyl)amino)propyl)-1-oxo-1H-isochromene-3-carboxamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X(18)32443-4.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

EPZ020411

EPZ020411 is a potent, selective PRMT6 inhibitor with IC50 of 10 nM.
MM-401

A potent inhibitor of MLL1/WDR5 protein-protein interaction with IC50 of 0.9 nM.
WDR5-MLL1 inhibitor

WDR5-MLL1 inhibitor is a novel potent inhibitor of WDR5-MLL1 interaction, binds to WDR5 with Kd of 1 nM.

Sign In Join Free