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LDC7559
CAS No. 2407782-01-6
LDC7559( —— )
Catalog No. M26276 CAS No. 2407782-01-6
LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 177 | Get Quote |
|
| 10MG | 295 | Get Quote |
|
| 25MG | 502 | Get Quote |
|
| 50MG | 709 | Get Quote |
|
| 100MG | 1008 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLDC7559
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NoteResearch use only, not for human use.
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Brief DescriptionLDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.
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DescriptionLDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.(In Vitro):LDC7559 (1 and 5 μM) inhibits IL-1β release upon inflammasome activation, and significantly blocks the lethal effect of both human and murine GSDMD NT domains transfected into HEK293T cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorVHL
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Research Area——
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Indication——
Chemical Information
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CAS Number2407782-01-6
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Formula Weight349.38
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Molecular FormulaC20H19N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (286.22 mM)
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SMILESO=C(NC1=CC=C2C(OCC3=CC(=NN3C2)C=4C=CC=CC4OC)=C1)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.
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