L755507

CAS No. 159182-43-1

L755507( L-755507 | L 755507 | L755507 )

Catalog No. M17337 CAS No. 159182-43-1

L755507 is an effective, selective agonist of β3-AR(IC50=35 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 98 In Stock
10MG 158 In Stock
25MG 282 In Stock
50MG 421 In Stock
100MG 606 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    L755507
  • Note
    Research use only, not for human use.
  • Brief Description
    L755507 is an effective, selective agonist of β3-AR(IC50=35 nM).
  • Description
    L-755507 is a potent β3-adrenergic receptor partial agonist > 1000-fold selective over β1- and β2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human β3-, β1- and β2-adrenoceptors respectively). L-755507 stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    L-755507 | L 755507 | L755507
  • Pathway
    Tyrosine Kinase
  • Target
    Bcr-Abl
  • Recptor
    β1-adrenergic receptor| β2-adrenergic receptor| β2-adrenergic receptor
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    159182-43-1
  • Formula Weight
    584.73
  • Molecular Formula
    C30H40N4O6S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 125 mg/mL. 213.77 mM;
  • SMILES
    CCCCCCNC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)COc2ccc(O)cc2)cc1
  • Chemical Name
    1-hexyl-3-[4-[[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]sulfamoyl]phenyl]urea

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yu C, et al. Cell Stem Cell. 2015, 16(2):142-147.
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