L-Tryptophan

Research use only, not for human use.

An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults.

An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.

Cell Viability Assay Cell Line:pTr2 cell Concentration:500, 1000 μM Incubation Time:48 h Result:500 and 1000 μM groups had decreased cell viability by 7% and 22%, respectively, at 48 h posttreatment.Cell Cycle Analysis Cell Line:pTr2 cell Concentration:500, 1000 μM Incubation Time:48 h Result:The percentage of pTr2 cells in the G1 phase increased from 65.70% (control) to 71.37% (500 mM) and 73.86% (1000 mM).Cell Migration Assay Cell Line:hBMSCs Concentration:10 μM Incubation Time:For three weeks Result:Exhibited a higher ability for migration than the control group.RT-PCR Cell Line:hBMSCs Concentration:10 μM Incubation Time:For three weeks Result:Decreased mRNA levels of adipogenic markers PPARγ and LPL.

Animal Model:Five-week-old C57BL/6 miceDosage:10, 50 kg/mg Administration:Intraperitoneally; daily; for consecutive three weeks Result:The concentration of 50 mg/kg/day induced a significant increase in the number of SSEA-4 positive cells. Increased the mRNA levels of Nanog and Oct-4 and the colony-forming ability of mBMSCs with 50 mg/kg/day.

Tryptophan | NSC 13119 | NSC-13119 | NSC13119 | Ardeytropin | L-Tryptophane

Immunology/Inflammation

Amino Acids and Derivatives

Amino Acids and Derivatives

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73-22-3

204.23

C11H12N2O2

>98% (HPLC)

soluble in Water

O=C(O)C(N)CC1=CNC2=C1C=CC=C2

tryptophan

(-20℃)

With Ice Pack

≥ 2 years