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Home - Products - Proteasome/Ubiquitin - Endogenous Metabolite - L-Kynurenine

L-Kynurenine

CAS No. 2922-83-0

L-Kynurenine( (S)-Kynurenine )

Catalog No. M19725 CAS No. 2922-83-0

L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    L-Kynurenine
  • Note
    Research use only, not for human use.
  • Brief Description
    L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.
  • Description
    L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    (S)-Kynurenine
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite|AhR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2922-83-0
  • Formula Weight
    208.21
  • Molecular Formula
    C10H12N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (240.14 mM) Need ultrasonic;Water:4mg/mL(at 20°C);0.5M HCL:50mg/mL
  • SMILES
    N[C@@H](CC(=O)c1ccccc1N)C(O)=O
  • Chemical Name
    (S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kolho K L Pessia A Jaakkola T et al. Faecal and serum metabolomics in paediatric inflammatory bowel disease[J]. Journal of Crohns & Colitis 2017 11(3):321-334.
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