L-JNKI-1
CAS No.
L-JNKI-1 ( )
Catalog No. M30052 CAS No.
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameL-JNKI-1
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NoteResearch use only, not for human use.
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Brief DescriptionL-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.
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DescriptionL-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies. (In Vivo):L-JNKI-1 has been shown to effectively inhibit JNK activity in in vivo studies. It is shown that Ang II induces a dose-dependent pressor response, which was significantly attenuated by JNK inhibition. It is also found that 10 μM L-JNKI-1 decreases phosphorylated c-Jun by 98% and phosphorylated Elk-1 by 100%. L-JNKI-1 is able to across the blood-brain barrier and penetrate neurons of adult mice and P5 rats within 1 h after an intraperitoneal injection.
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Synonyms
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PathwayOthers
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TargetOther Targets
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RecptorJNK
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Research Area——
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Indication——
Chemical Information
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CAS Number--
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Formula Weight3822.4
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Molecular FormulaC164H286N66O40
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Purity>98% (HPLC)
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SolubilityH2O : ≥ 100 mg/mL (26.16 mM)
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SMILES——
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Chemical Name
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Zhou MS, et al. Role of c-Jun N-terminal kinase in the regulation of vascular tone. J Cardiovasc Pharmacol Ther. 2010 Mar;15(1):78-83.
molnova catalog
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