L-JNKI-1
CAS No.
L-JNKI-1 ( )
Catalog No. M30052 CAS No.
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NameL-JNKI-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionL-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.
-
DescriptionL-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies. (In Vivo):L-JNKI-1 has been shown to effectively inhibit JNK activity in in vivo studies. It is shown that Ang II induces a dose-dependent pressor response, which was significantly attenuated by JNK inhibition. It is also found that 10 μM L-JNKI-1 decreases phosphorylated c-Jun by 98% and phosphorylated Elk-1 by 100%. L-JNKI-1 is able to across the blood-brain barrier and penetrate neurons of adult mice and P5 rats within 1 h after an intraperitoneal injection.
-
Synonyms
-
PathwayOthers
-
TargetOther Targets
-
RecptorJNK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number--
-
Formula Weight3822.4
-
Molecular FormulaC164H286N66O40
-
Purity>98% (HPLC)
-
SolubilityH2O : ≥ 100 mg/mL (26.16 mM)
-
SMILES——
-
Chemical Name
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Zhou MS, et al. Role of c-Jun N-terminal kinase in the regulation of vascular tone. J Cardiovasc Pharmacol Ther. 2010 Mar;15(1):78-83.
molnova catalog
related products
-
Yubeinine
Yubeinine is an alkaloid natural product possessing tracheal relaxant effects.
-
Tessaric acid
Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.
-
Testosterone acetate
Testosterone acetate is a hormone with in vitro antitumor activity.